The primary outcome measure was survival to hospital discharge. Patients who had a traumatic cardiac arrest, do-not-resuscitate medical directives, or cardiac arrest due to drowning, hypothermia, hanging, or suspected drug overdose were excluded from the study. Patients who were at least 18 years of age and had an out-of-hospital cardiac arrest and refractory ventricular fibrillation of presumed cardiac cause were eligible for the study.
#Sequential defibrillation trial
In-Depth :This three-group, cluster-randomized, controlled trial with crossover was conducted in six paramedic services in Canada from March 2018 to May 2022. Relevant Reading: Long-Term Outcomes of Out-of-Hospital Cardiac Arrest after Successful Early Defibrillation Nevertheless, the study’s findings are significant, as they demonstrate that DSED and VC defibrillation provide a higher survival to hospital discharge among patients with refractory ventricular fibrillation during out-of-hospital cardiac arrest. This study was limited by not specifying a fixed follow-up time, and the length of stay distributions across the trial centers is unknown. Overall, this study found that survival to hospital discharge was higher with DSED and VC defibrillation as compared to standard defibrillation in patients with refractory ventricular fibrillation. However, there is a gap in knowledge regarding the effectiveness of DSED and VC defibrillation compared with standard defibrillation in patients who remain in refractory ventricular fibrillation during out-of-hospital cardiac arrest. DSED and VC have been proposed to provide potential benefits in defibrillating a portion of the ventricle that may not be completely defibrillated by pads in the standard anterior-lateral position. Almost half of these patients may remain in refractory ventricular fibrillation despite multiple defibrillation attempts. Study Rundown: There are over 350,000 unexpected deaths each year in North America due to out-of-hospital cardiac arrest, with 100,000 of these cases attributed to ventricular fibrillation or pulseless ventricular tachycardia.
0 kommentar(er)
